The Wesleyan Mission Society arrived in Ghana in 1835. Since then, the Methodist Church has been involved in the provision and development of high quality education at the basic, senior secondary and teacher training levels.

The role of Churches, including the Methodist Church, in providing basic, secondary and teacher education was reduced in 1961 under the then educational reform programme. The Government decided to be responsible for running the mission schools and training colleges. It also established many secondary schools and training colleges. Currently, Ghana has six state universities: University of Ghana, Kwame Nkrumah University of Science and Technology, University of Cape Coast, University of Education Winneba, University for Development Studies and University of Mines and Technology, Tarkwa.

Despite the existence of these six institutions, considerable concern has been expressed about the inadequacy of the institutional facilities in the universities to cater for qualified candidates to avail themselves of the opportunity for tertiary education. The Methodist Church Ghana was convinced that with her unique record and experience in the provision of education at the basic, secondary and teacher education levels, it could make a contribution to the solution of the problems of offering education at all levels.

The Church decided at its 36th Annual Conference held in Cape Coast (1997) to establish a Methodist University College. After due preparations and processes, the Methodist University College Ghana (MUCG) was granted accreditation by the National Accreditation Board in August 2000. Its application for affiliation to the University of Ghana was approved in October 2002. MUCG started academic work in October, 2000.
The first batch of students reported for lectures in November, 2000, the" second batch in October, 2001. The University College has just completed its tenth academic year.